University of Oklahoma researcher leads efforts to unravel mysteries of cognitive decline

An estimated 76,000 Oklahomans are living with Alzheimer’s disease, a number that has surged by 13% in just five years. Yet, despite the increasing need for effective treatments, therapies for age-related dementia have largely failed to slow or halt the disease’s progression. Now, a University of Oklahoma researcher, backed by $2.2 million in federal funding,… Continue reading University of Oklahoma researcher leads efforts to unravel mysteries of cognitive decline

Acute Communication Between Microglia and Nonparenchymal Immune Cells in the Anti-A{beta} Antibody-Injected Cortex

Anti-Aβ immunotherapy use to treat Alzheimer’s disease is on the rise. While anti-Aβ antibodies provide hope in targeting Aβ plaques in the brain, there still remains a lack of understanding regarding the cellular responses to these antibodies in the brain. In this study, we sought to identify the acute effects of anti-Aβ antibodies on immune… Continue reading Acute Communication Between Microglia and Nonparenchymal Immune Cells in the Anti-A{beta} Antibody-Injected Cortex

TWiV 1187: The tau of herpesvirus

TWiV explains a new blood test for head and neck cancer, Japanese regulators approve tecovirimat for mpox, an entry receptor for enterovirus D68, and anti-herpetic tau preserves neurons via a DNA sensing pathway in Alzheimer’s disease. Hosts: Vincent Racaniello, Kathy Spindler, Brianne Barker, and Angela Mingarelli Click arrow to playDownload TWiV 1187 (70 MB .mp3, 117… Continue reading TWiV 1187: The tau of herpesvirus