Tag: Allergy and Hypersensitivity

Immune 87: When the immune system misbehaves

Immune discusses basophils as regulators of of lung inflammation over space and time, and neoself-antigens as the primary target for autoreactive T cells in human lupus. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Click arrow to playDownload Immune 87 (100 MB .mp3, 69 min)Subscribe (free): Apple Podcasts, RSS, emailBecome a patron of Immune! Links for this episode MicrobeTV Discord… Continue reading Immune 87: When the immune system misbehaves

How stress fuels allergic skin inflammation

Psychological stress weakens the ability of certain immune cells to clear away dead cells, causing a buildup that triggers more inflammation and worsens allergic reactions Study: Stress-experienced monocytes/macrophages lose anti-inflammatory function via β2-adrenergic receptor in skin allergic inflammation. Image Credit: savitskaya iryna / Shutterstock.com A recent Journal of Allergy and Clinical Immunology study investigates the cellular… Continue reading How stress fuels allergic skin inflammation

Stress-induced immune dysfunction linked to worsened skin allergies

Psychological stress is known to exacerbate skin allergies, but the underlying molecular mechanisms remain poorly understood. Recent studies using a mouse model of immunoglobulin E (IgE)-mediated cutaneous allergic inflammation (IgE-CAI) suggest that stress may disrupt immune functions, thereby worsening allergic symptoms by interfering with the body’s inflammatory responses. IgE-CAI is characterized by swelling and infiltration… Continue reading Stress-induced immune dysfunction linked to worsened skin allergies