Allogeneic hematopoietic cell transplantation (allo-HCT) is the only cure for acute myeloid leukemia (AML) in second complete remission (CR2) Patients lacking a matched sibling donor (MSD) receive transplants from mismatched unrelated donors .
Tag: Adaptive Immunity
B cells: The many facets of B cells in allergic diseases
Differential regulation of IL-17A and IL-17F via STAT5 contributes to psoriatic disease
Four researchers with MIT ties earn 2023 Schmidt Science Fellowships
AI SummaryFour researchers with ties to MIT have been named Schmidt Science Fellows. Lillian Chin, Neil Dalvie, Suong Nguyen, and Yirui Zhang are among the 32 exceptional early-career scientists worldwide chosen to receive the prestigious fellowships. They will receive a stipend of $100,000 a year for up to two years of postdoctoral research in a… Continue reading Four researchers with MIT ties earn 2023 Schmidt Science Fellowships
IgG:FcγRIIb signals block effector programs of IgE:FcεRI-activated mast cells but spare survival pathways
Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy
Human small intestine contains 2 functionally distinct regulatory T-cell subsets
Distinct dynamics of antigen-specific induction and differentiation of different CD11c+Tbet+ B-cell subsets
Researchers map brain cell changes in Alzheimer’s disease
AI SummaryResearchers at the Broad Institute of MIT and Harvard have developed a new method called STARmap PLUS to study the relationship between protein buildup and the death of neurons in Alzheimer’s disease using a mouse model. The technique allows for the simultaneous mapping of gene expression and the spatial distribution of proteins in intact… Continue reading Researchers map brain cell changes in Alzheimer’s disease