Dr Annalisa Morgan previews discussions on disease-modifying therapies, emerging treatments such as CAR T-cell therapy, and the challenges of managing MS in older patients. Medscape
Tag: Adaptive Immunity
ACTRIMS 2025: Anticipating New Directions in DMTs for RRMS
Dr Annalisa Morgan previews discussions on disease-modifying therapies, emerging treatments such as CAR T-cell therapy, and the challenges of managing MS in older patients. Medscape
Groundbreaking study shows potential of new mRNA vaccine to help fight tuberculosis
A new vaccine that boosts immunity against tuberculosis (TB) has been shown to be effective in pioneering pre-clinical trials.
Targeting the future: Antibody-Drug Conjugates (ADCs) in platinum-sensitive ovarian cancer in the post-PARP era
Platinum-based chemotherapy remains a cornerstone in the treatment of platinum-sensitive ovarian cancer (PSOC) due to its demonstrated efficacy in prolonging progression-free survival (PFS).1-3 Retreatment with platinum agents, especially in patients who have been exposed to poly ADP-ribose polymerase inhibitors (PARPi) presents challenges with respect to both efficacy and toxicity. Recently, novel targeted therapies, including antibody-drug… Continue reading Targeting the future: Antibody-Drug Conjugates (ADCs) in platinum-sensitive ovarian cancer in the post-PARP era
Scientists identify a new cancer immunotherapy target: Dysfunctional B cells
Scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood — known as the tertiary lymphoid structure — where they become frustratingly dysfunctional when in close contact with tumors.
[ASAP] Retraction of “Development and Immunological Evaluation of a Multiantigen Thermostable Nanovaccine Adjuvanted with T-Cell-Activating Scaffold for African Swine Fever”
ACS Applied Bio MaterialsDOI: 10.1021/acsabm.5c00194
Unlocking the potential of double negative memory B cells in cancer treatment
University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood – known as the tertiary lymphoid structure – where they become frustratingly dysfunctional when in close contact with tumors. Described today in the journal Science Translational Medicine,… Continue reading Unlocking the potential of double negative memory B cells in cancer treatment
Cell-based glycoengineering for production of homogeneous and specific glycoform-enriched antibodies with improved effector functions
Molecular mimicry-driven autoimmunity in chronic rhinosinusitis with nasal polyps
Seeing more in expansion microscopy
In biology, seeing can lead to understanding, and researchers in Edward Boyden’s lab at MIT’s McGovern Institute are committed to bringing life into sharper focus. With a pair of new methods, they are expanding the capabilities of expansion microscopy—a high-resolution imaging technique the group introduced in 2015—so researchers everywhere can see more when they look… Continue reading Seeing more in expansion microscopy