Trial By Error: Usual Suspects Say NICE Made Eight Errors; Nonsense, Says Committee Member Adam Lowe

By David Tuller, DrPH Update Jan 5, 2023: Martin Rücker, the German investigative journalist who posted the snippets from the draft article, touched base after seeing this post and assured me that the copy he received was not a formally embargoed version provided to reporters before publication. In other words, no embargo was broken, as… Continue reading Trial By Error: Usual Suspects Say NICE Made Eight Errors; Nonsense, Says Committee Member Adam Lowe

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TWiV 966: 1918 influenza with Jeffery Taubenberger

Vincent travels to the NIH campus to speak with Jeffery Taubenberger about his career, the 1918 influenza pandemic, deciphering the genome sequence of the virus from tissues of disease victims and using it to rescue infectious virus.

Trial By Error: Can Functional Neurological Disorder Be an Indication of Prion Disease?

By David Tuller, DrPH A recent article in the Journal of Neurology presents a twist on the issue of functional neurological disorder (FND). The article, which was published in September, is called “Functional neurological symptoms as initial presentation of Creutzfeldt‐Jakob disease: case series.” Creutzfeldt-Jakob disease is a prion disorder that leads to dementia and death,… Continue reading Trial By Error: Can Functional Neurological Disorder Be an Indication of Prion Disease?

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Trial By Error: A Stupid Study of Exercise for Long Covid Patients With Post-Exertional Symptom Exacerbation

By David Tuller, DrPH The Journal of Medical Virology has just published a study called “Effect of using a structured pacing protocol on post-exertional symptom exacerbation and health status in a longitudinal cohort with the post-COVID-19 syndrome.” The investigators are from the University of Leeds and the Leeds Community Healthcare NHS Trust. Post-COVID-19 syndrome (PCS)… Continue reading Trial By Error: A Stupid Study of Exercise for Long Covid Patients With Post-Exertional Symptom Exacerbation

Trial By Error: Is the Long Covid Phenomenon an Expression of “Psychosocial Distress”?

By David Tuller, DrPH For the second time in a few weeks, a major US news organization has provided Professor Michael Sharpe, lead PACE investigator and one-time Virology Blog commenter, with a high-profile platform to disseminate his typical blather and nonsense. Both articles—the first in New York Magazine, the second in The New Republic–-have presented… Continue reading Trial By Error: Is the Long Covid Phenomenon an Expression of “Psychosocial Distress”?

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Trial By Error: Top Lightning Process Proponent Privately Lobbied for Approval of Norway’s LP Study

By David Tuller, DrPH *Two corrections had been made in the text below. The NEM committee has 12 members, not nine, as I originally wrote. And when Dr Flottorp wrote her letter, it was not while the NEM committee was considering the proposed Lightning Process trial, as I originally wrote, but before it had progressed… Continue reading Trial By Error: Top Lightning Process Proponent Privately Lobbied for Approval of Norway’s LP Study

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Trial By Error: Recent Articles in The Guardian, CNBC and Popular Science

By David Tuller, DrPH As part of an ongoing project on long Covid, The Guardian recently published a powerful excerpt from a book called “What Doesn’t Kill Us Makes Us: Who We Become After Tragedy and Trauma.” The author, Mike Mariani, is an American journalist who a decade ago found himself smacked with a debilitating… Continue reading Trial By Error: Recent Articles in The Guardian, CNBC and Popular Science

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“Paxlovid Rebound” Is Just COVID Rebound

by Gertrud U. Rey The antiviral drug Paxlovid is highly effective at inhibiting SARS-CoV-2 replication and reducing symptoms associated with COVID-19. Nevertheless, there have recently been numerous reports of recurrence of positive tests and symptoms after completing treatment with Paxlovid, leading some to infer that the drug triggers the recurrence. Is this inference actually correct,… Continue reading “Paxlovid Rebound” Is Just COVID Rebound