Ten-year study shows tomosynthesis improves breast cancer detection

AI SummarySummary: A 10-year study found that using digital breast tomosynthesis (DBT) for breast cancer screening improves the detection rates and reduces the rate of advanced cancers compared to conventional 2D digital mammography.According to a new 10-year study, screening for breast cancer with digital breast tomosynthesis (DBT) increases cancer detection rates and significantly reduces the… Continue reading Ten-year study shows tomosynthesis improves breast cancer detection

New Study Finds Higher County-Level Jail and State-Level Prison Incarceration Rates Associated With Higher County- and State-Level Cancer Mortality Rates

AI SummaryThis study suggests a correlation between higher rates of incarceration at the county and state levels and increased cancer mortality rates. Researchers recommend implementing programs to address the negative health impacts of mass incarceration to reduce cancer disparities.American Cancer Society researchers stress programs to address adverse health effects of mass incarceration are needed to… Continue reading New Study Finds Higher County-Level Jail and State-Level Prison Incarceration Rates Associated With Higher County- and State-Level Cancer Mortality Rates

Basal/squamous and Mixed subtype bladder cancers present poor outcomes after neoadjuvant chemotherapy in the VESPER trial

AI SummaryThis article discusses the poor outcomes of basal/squamous and mixed subtype bladder cancers after neoadjuvant chemotherapy in the VESPER trial. It highlights the need for predictive biomarkers for response or chemoresistance in muscle-invasive bladder cancer, with gene expression-based subtypes being considered as potential markers. The response of the basal subtype to chemotherapy is a… Continue reading Basal/squamous and Mixed subtype bladder cancers present poor outcomes after neoadjuvant chemotherapy in the VESPER trial

Immunotherapy shows promise for men with specific types of prostate cancer

AI SummarySummary: Immunotherapy has shown promise in treating specific types of prostate cancer by slowing down disease progression in men with certain genetic characteristics. In a recent study, the progression of the disease was delayed by 33 months in these individuals.New research has shown that immunotherapy can be effective in treating prostate cancer in men… Continue reading Immunotherapy shows promise for men with specific types of prostate cancer

Study links neighborhood environment to prostate cancer risk in men with West African genetic ancestry

AI SummaryThe study explores the association between West African genetic ancestry and prostate cancer risk in men living in different neighborhood environments. It suggests that neighborhood disadvantage may impact the relationship between genetic ancestry and prostate cancer risk. This research highlights the importance of considering both genetic and environmental factors in understanding health disparities.West African… Continue reading Study links neighborhood environment to prostate cancer risk in men with West African genetic ancestry

Smoking prevalence and association with sociodemographic variables in cancer clinical trial participants

AI SummaryThis study examines smoking prevalence and its association with sociodemographic variables in cancer clinical trial participants. Nearly half of the 4326 patients enrolled in 29 trials reported ever smoking, with one in six reporting current or recent smoking. Factors associated with smoking included male gender, older age, Medicaid or no insurance, high socioeconomic deprivation,… Continue reading Smoking prevalence and association with sociodemographic variables in cancer clinical trial participants

NIH study links neighborhood environment to prostate cancer risk in men with West African genetic ancestry

AI SummarySummary: The study highlights that living in a disadvantaged neighborhood increases the risk of prostate cancer in men with West African genetic ancestry. Chronic stress from various sources like racial profiling and housing discrimination is believed to contribute to this heightened risk.A new study suggests, for men with West African genetic ancestry, living in… Continue reading NIH study links neighborhood environment to prostate cancer risk in men with West African genetic ancestry

Immunotherapy after surgery helps people with high-risk bladder cancer live cancer-free longer

AI SummaryThis article discusses the results of an NCI trial indicating that administering pembrolizumab to patients after surgery for high-risk muscle invasive bladder cancer can double the median length of time they remain cancer-free compared to observation alone after surgery. This finding underscores the potential benefits of immunotherapy in treating high-risk bladder cancer patients.An NCI… Continue reading Immunotherapy after surgery helps people with high-risk bladder cancer live cancer-free longer

Safety and clinical activity of BMS-986365 (CC-94676), a dual androgen receptor ligand-directed degrader and antagonist, in heavily pretreated patients with metastatic castration-resistant prostate cancer

AI SummaryIn this study, the safety and clinical activity of BMS-986365 (CC-94676), a dual androgen receptor ligand-directed degrader and antagonist, is examined in heavily pretreated patients with metastatic castration-resistant prostate cancer (mCRPC). The drug targets the androgen receptor via a unique mechanism of AR degradation and antagonism. The study, known as CC-94676-PCA-001 (NCT04428788), is a… Continue reading Safety and clinical activity of BMS-986365 (CC-94676), a dual androgen receptor ligand-directed degrader and antagonist, in heavily pretreated patients with metastatic castration-resistant prostate cancer