AI SummaryHampel et al. review data on Alzheimer’s disease biomarkers that are close to clinical use and discuss important factors for their development and implementation.Hampel et al. review current data on blood-based biomarkers (BBBMs) for Alzheimer’s disease (AD) that are closest to clinical adoption, discussing important concepts and considerations for the development and implementation of AD… Continue reading Blood-based biomarkers for Alzheimer’s disease: Current state and future use in a transformed global healthcare landscape
Category: Neuroscience
From labs to the streets, experts work to defuse childhood threats to mental health
AI SummaryThreats to child mental health, such as poverty, abuse, and pollution, were discussed by experts at a symposium at MIT, who stressed the importance of science and research in addressing these issues. The speakers highlighted various mechanisms that connect early life experiences to mental health problems, as well as interventions and programs aimed at… Continue reading From labs to the streets, experts work to defuse childhood threats to mental health
40 Hz vibrations reduce Alzheimer’s pathology, symptoms in mouse models
AI SummaryEvidence from a new study conducted by MIT scientists demonstrates that noninvasive tactile stimulation at a frequency of 40 Hz can improve brain health and motor function in mice models of Alzheimer’s disease, while also reducing levels of phosphorylated tau protein, preventing neuron death, and reducing neural DNA damage. The study suggests that tactile… Continue reading 40 Hz vibrations reduce Alzheimer’s pathology, symptoms in mouse models
New perspectives in diabetic neuropathy
Eid et al. review the current state of knowledge of diabetic peripheral neuropathy, emphasizing how hyperglycemia and dyslipidemia, against the backdrop of the unique peripheral nerve anatomy, drive bioenergetics failure and injury. Axoglial interactions, pain mechanisms, and rationale-based treatment approaches are also covered.
[In Context] Kerstin Hellwig: educating on multiple sclerosis and pregnancy
AI SummaryKerstin Hellwig, a clinician-scientist, had various aspirations as a child before settling on becoming a doctor. She now specializes in multiple sclerosis and pregnancy. Hellwig is the chair and founder of the German multiple sclerosis and pregnancy registry and has a private practice.When Kerstin Hellwig was 3 years old, she wanted to become a… Continue reading [In Context] Kerstin Hellwig: educating on multiple sclerosis and pregnancy
From molecular to whole-brain scale in a simple animal, study reveals serotonin’s effects
AI SummaryResearchers at The Picower Institute for Learning and Memory at MIT have conducted a comprehensive study on how serotonin affects behavior in the nematode worm C. elegans, which has similarities to the human brain. The study provides insights into the role of serotonin receptors and their complex interactions in controlling behavior, which could enhance… Continue reading From molecular to whole-brain scale in a simple animal, study reveals serotonin’s effects
3 Questions: A new model of nervous system form, function, and evolution
How does animal behavior emerge from networks of connected neurons? How are these incredible nervous systems and behaviors actually generated by evolution? Are there principles shared by all nervous systems or is evolution constantly innovating? What did the first nervous system look like that gave rise to the incredible diversity of life that we see… Continue reading 3 Questions: A new model of nervous system form, function, and evolution
3 Questions: Sara Prescott on the brain-body connection
AI SummarySara Prescott, a faculty member in the Department of Biology at MIT, is researching the interoceptive nervous system and its role in detecting and responding to stimuli in the body. Her focus is on the mammalian airway and how neural pathways affect respiratory function and overall health. The goal of her research is to… Continue reading 3 Questions: Sara Prescott on the brain-body connection
Four researchers with MIT ties earn 2023 Schmidt Science Fellowships
AI SummaryFour researchers with ties to MIT have been named Schmidt Science Fellows. Lillian Chin, Neil Dalvie, Suong Nguyen, and Yirui Zhang are among the 32 exceptional early-career scientists worldwide chosen to receive the prestigious fellowships. They will receive a stipend of $100,000 a year for up to two years of postdoctoral research in a… Continue reading Four researchers with MIT ties earn 2023 Schmidt Science Fellowships
Scientists discover how mutations in a language gene produce speech deficits
AI SummaryMutations in the gene Foxp2 have been linked to speech disorders, specifically apraxia. Researchers from MIT and National Yang Ming Chiao Tung University conducted a study on mice and found that these mutations disrupt the formation of dendrites and neuronal synapses in the brain, affecting the ability to produce high-frequency sounds. The mutations prevent… Continue reading Scientists discover how mutations in a language gene produce speech deficits