Will OCEANIC-AF Sink Factor XI Inhibitors?

Cardiologists Michelle O’Donoghue and Manesh Patel discuss the disappointing findings for the factor XIa inhibitor asundexian from the OCEANIC-AF trial presented at ESC. theheart.org on Medscape

Loneliness: Time for Medicine to Address This Risk Factor

AI SummaryThe article discusses the connection between loneliness and health, emphasizing the need for clinicians to assess and address loneliness as a significant risk factor. This highlights the importance of recognizing and addressing social determinants of health in medical practice for overall well-being.Indu Subramanian and Julianne Holt-Lunstad discuss the connection between loneliness and health, and… Continue reading Loneliness: Time for Medicine to Address This Risk Factor

Untreated Brain Aneurysms Raise Mental Illness Risk

AI SummaryThis article discusses a study linking untreated unruptured intracranial aneurysms to a 10% higher risk for mental illness, particularly in younger individuals and those needing psychotherapy. The research highlights the importance of timely treatment of brain aneurysms to prevent potential mental health complications.Untreated unruptured intracranial aneurysms were linked to a 10% higher risk for… Continue reading Untreated Brain Aneurysms Raise Mental Illness Risk

How Gut Health May Affect Alzheimer’s and Parkinson’s

AI SummaryThis article discusses how disturbances in the microbiome may impact the onset and severity of Alzheimer’s and Parkinson’s diseases. Research is being conducted to determine if mitigating these disturbances can slow or reverse the progression of these neurodegenerative diseases.Research into these neurodegenerative diseases is exploring how disturbances in our microbiome might influence their onset… Continue reading How Gut Health May Affect Alzheimer’s and Parkinson’s

Finding some stability in adaptable brains

AI SummaryThe content discusses the balance in the brain between stability and flexibility, focusing on individual neurons and synapses in the sensory cortex. Pyramidal neurons have both stable and flexible synapses, with some synapses losing their flexibility by adulthood. The study reveals that stable synapses in a specific region of these neurons have unique properties… Continue reading Finding some stability in adaptable brains

ALS Blood Test Promises Accurate, Earlier Diagnosis

AI SummaryThis article discusses a new blood test that can accurately identify patients with amyotrophic lateral sclerosis (ALS) at early stages, potentially leading to quicker diagnosis and treatment.A blood test has been shown to accurately identify patients with amyotrophic lateral sclerosis at early stages, which could speed diagnosis and treatment. Medscape Medical News

Dorsal root ganglion inflammation by oxaliplatin toxicity: DPEP1 as possible target for peripheral neuropathy prevention

Peripheral neuropathy (PN) constitutes a dose-limiting side effect of oxaliplatin chemotherapy that often compromises the efficacy of antineoplastic treatments. Sensory neurons damage in dorsal root ganglia (D…