From SLB22 on the Island of Hawai’i, Julia and Musa join Immune to reveal their remarkable career paths, and their research on understanding trained innate immunity. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Guests: Julia Bohannon and Musa Mhlanga Click arrow to playDownload Immune 61 (46 MB .mp3, 77 min)Subscribe (free): Apple Podcasts, Google Podcasts. RSS, emailBecome a patron of Immune! Links… Continue reading Immune 61: Training immune cells with Julia Bohannon and Musa Mhlanga
Category: Immunology
Immune 60: Immunoeducation with Sumali Pandey and Phil Mixter
Sumali and Phil join Immune to discuss their approaches to immunology education. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Guest: Sumali Pandey and Phil Mixter Click arrow to playDownload Immune 60 (46 MB .mp3, 77 min)Subscribe (free): Apple Podcasts, Google Podcasts. RSS, emailBecome a patron of Immune! Links for this episode ImmunoReach 44:04 ASMCUE: ASM Conference for Undergraduate Educators (ASMCUE) 18:51 Upcoming… Continue reading Immune 60: Immunoeducation with Sumali Pandey and Phil Mixter
Immune 59: Forks in the road: Th17 cells with Mandy McGeachy
At Cornell University in Ithaca, NY, Mandy joins Immune to discuss her career and her research on understanding how Th17 cells develop and are influenced to be ‘good’ or ‘bad’ in their function. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Guest: Mandy McGeachy Click arrow to playDownload Immune 59 (46 MB .mp3, 77 min)Subscribe (free): Apple… Continue reading Immune 59: Forks in the road: Th17 cells with Mandy McGeachy
Decreased ATM causing defective DNA repair and apoptosis in CVID
Reference: Hargreaves, C.E., Salatino, S., Sasson, S.C. et al. Decreased ATM Function Causes Delayed DNA Repair and Apoptosis in Common Variable Immunodeficiency Disorders. J Clin Immunol (2021). https://doi.org/10.1007/s10875-021-01050-2 Bottom line: Decreased pATM promotes DNA repair defects and promotes apoptosis. Complex CVID and Infections CVID have a differential expression of genes TOP3A, XRCC2, and MSH6. Continue Reading
Genetic plymorphisms in IFNL3/IFNL4 and its association with increased risk and earlier occurrence of several common infections in African children
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Interim Update on Novel Inborn Errors of Immunity
Reference: Tangye, S.G., Al-Herz, W., Bousfiha, A. et al. The Ever-Increasing Array of Novel Inborn Errors of Immunity: an Interim Update by the IUIS Committee. J Clin Immunol (2021). https://doi.org/10.1007/s10875-021-00980-1 Continue Reading
DADA2 deficiency with fulminant EBV infection
Reference: Brooks, J.P., Rice, A.J., Ji, W. et al. Uncontrolled Epstein-Barr Virus as an Atypical Presentation of Deficiency in ADA2 (DADA2). J Clin Immunol (2021). https://doi.org/10.1007/s10875-020-00940-1 Continue Reading
A case of SAVI with Splenic dysfunction and Specific Polysaccharide Antibody Deficiency
Reference: Bijker, E.M., Rösler, B., Hoppenreijs, E. et al. Functional Asplenia and Specific Polysaccharide Antibody Deficiency in a Girl with SAVI. J Clin Immunol (2020). Continue Reading
PID and role of Next-generation sequencing in India
Reference: Arunachalam, A.K., Maddali, M., Aboobacker, F.N. et al. Primary Immunodeficiencies in India: Molecular Diagnosis and the Role of Next-Generation Sequencing. J Clin Immunol (2020). https://doi.org/10.1007/s10875-020-00923-2 Continue Reading
October Update for Inborn Errors of Immunity
40 PUBMED indexed articles were published in the month of October 2020 on PID. New Inborn Error of Immunity Beck et al report a novel auto-inflammatory syndrome associated somatic mutations in UBA1 presenting in adulthood with a severe phenotype COVID-19 and PID Mantravadi et al report the recovery of X-CGD who had T cell lymphopenia… Continue reading October Update for Inborn Errors of Immunity