In a preprint* research paper recently uploaded to the bioRxiv server, researchers at Washington University investigated how the exposome can mediate immune function in house mice, one of the most widely used model systems for in vivo immunological experimentation. Mice were sequentially inoculated with six different viral pathogens from early life (neonatal) stages, following which… Continue reading Early viral exposure in mice weakens vaccine response, raising questions for human studies
Category: Immunology
Topical treatments for atopic dermatitis (eczema): systematic review and network meta-analysis of randomized trials
New cause of Alzheimer’s, vascular dementia
Researchers have discovered a new avenue of cell death in Alzheimer’s disease and vascular dementia. The study reveals for the first time that a form of cell death known as ferroptosis — caused by a buildup of iron in cells — destroys microglia cells in cases of Alzheimer’s and vascular dementia.
Experts call for changes to how drugs are tested and labeled for people with obesity
A new opinion piece published in Health Affairs Forefront raises questions around current approaches to assess drug safety and effectiveness in people with obesity. The article sheds light on how increased body fat can modify the effects of drugs used to treat common conditions, in some cases rendering the drugs ineffective or unsafe for people… Continue reading Experts call for changes to how drugs are tested and labeled for people with obesity
New Research Explains Limitation of Immunotherapy Against Brain Tumors
Cancer is a deadly disease with multiple risk factors. Risk factors are dependent on the type of cancer and each one is treated differently. The heterogeneity of various cancers is the main reason there is no cure. Additionally, cancer evolves and can also come back after being treated and lying dormant for years. Therefore, it… Continue reading New Research Explains Limitation of Immunotherapy Against Brain Tumors
Cells Generate Immune Response Networks
Our immune system is made of various cell types responsible for fighting pathogens and disease that enter the body. There are two distinct arms or responses of the immune system: innate and adaptive. The innate immune response is the first line of defense that includes immune cells that are not specific to the invading pathogen,… Continue reading Cells Generate Immune Response Networks
