Author Correction: Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets

Correction to: Nature Immunology https://doi.org/10.1038/s41590-023-01588-w, published online 10 August 2023. In the version of the article originally published, the middle panel in Fig. 3b was mistakenly a duplicate of the upper panel. The figure has now been corrected in the HTML and PDF versions of the article. Author informationAuthor notes These authors contributed equally: Jing… Continue reading Author Correction: Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets

Published
Categorized as Immunology

CD8+ T cells pump the brakes on Alzheimer’s disease

A recent study identified a microglia–T cell communication axis that retains CD8+ T cells in brains with amyloid pathology. Data from this study indicate that CD8+ T cells restrict Alzheimer’s disease pathogenesis. Gone are the days of considering the brain an immune-privileged site that is isolated from the peripheral immune system. The presence of inflammatory… Continue reading CD8+ T cells pump the brakes on Alzheimer’s disease

How Immune Cells Can Make Their Own Movements More Effective

Immune cells have to respond to threats like invading pathogens and cancerous cells, and sometimes, they must push through tissues and move into tight spaces, and do it quickly. New work has shown that some immune cells have their own mechanisms to guide them through environments that are tough to navigate so they can reach… Continue reading How Immune Cells Can Make Their Own Movements More Effective

Published
Categorized as Immunology

Newly Discovered Brain Cell Type Has Extensive Abilities

New evidence of a hitherto undiscovered type of brain cell forces a reappraisal of our prior knowledge of the brain. The remarkable characteristics of this long-hypothesized cell type are detailed in a recent Nature paper.  The vast majority of cells in the human brain are astrocytes, not neurons. They support the activity of neurons by… Continue reading Newly Discovered Brain Cell Type Has Extensive Abilities

Published
Categorized as Immunology

Review identifies future research directions for the study of a SARS-CoV-2 reservoir in PASC

A recent study published in Nature Immunology reviewed the evidence for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reservoir in post-acute sequelae of coronavirus disease 2019 [COVID-19] (PASC). Study: SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC). Image Credit: Kateryna Kon/Shutterstock.com Some individuals infected with SARS-CoV-2 develop new symptoms or sequelae, which do not resolve… Continue reading Review identifies future research directions for the study of a SARS-CoV-2 reservoir in PASC