Science Immunology, Volume 8, Issue 87, September 2023.
Category: Immunology
Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells
Science Immunology, Volume 8, Issue 87, September 2023.
The role of glycosylation in clinical allergy and immunology
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Study explains why certain immunotherapies don’t always work as predicted
AI SummaryStudy finds reason why checkpoint blockade inhibitors are ineffective for some patients with highly mutated tumors.A study reveals a possible explanation for why checkpoint blockade inhibitors don’t work well for some patients whose tumors have a high mutational burden.
Specialized gut immune cells pinpointed that can limit progression of inflammatory bowel disease
AI SummaryResearchers have identified and studied a specific immune cell that helps protect and repair cells in the human gut.Researchers have characterized a specialized type of immune cell, which plays a key role in protecting and repairing the cells in the healthy human gut.
Tests Reveal Unreliability of Allergy Tests & Experts Call for Standardization
AI SummaryStandard skin prick tests (SPTs) used to diagnose allergies may not be reliable due to lack of standardization in allergen extracts. The tests can produce false negatives, putting people at risk. Standardization and improvements in blood tests are needed to improve accuracy. Further research is necessary to develop better allergy tests.Allergies can be extremely… Continue reading Tests Reveal Unreliability of Allergy Tests & Experts Call for Standardization
‘Night Owls’ are at Higher Risk of Developing Diabetes
AI SummaryResearchers at Brigham and Women’s Hospital found that going to bed late and waking up late is associated with a 19% increased risk of developing diabetes. This is independent of the amount of sleep a person gets and is more related to their sleep schedule and lifestyle habits. The study also found that individuals… Continue reading ‘Night Owls’ are at Higher Risk of Developing Diabetes
Proteins in Breast Milk Found to be Essential for Baby’s Gut
AI SummaryBreast milk contains proteins that can regulate the immune system and influence the composition of gut microbes in newborn babies, according to research conducted by Dr. Ignatius Man-Yau Szeto and his team at the Yili Maternal and Infant Nutrition Institute. The study suggests that these proteins play a critical role in early immunity and… Continue reading Proteins in Breast Milk Found to be Essential for Baby’s Gut
Multi-omics study offers insights into psoriasis treatment
AI SummaryA recent study found that blocking interleukin-17A can effectively treat psoriasis by suppressing autoimmune functions and reducing symptoms. This approach shows promise for developing a cure for psoriasis, a chronic autoimmune skin condition.In a recent study published in the journal Frontiers in Immunology, researchers use a multi-omics approach combining immune cell-enriched single-cell transcriptomics (scRNA-seq),… Continue reading Multi-omics study offers insights into psoriasis treatment
Antigen receptor signaling and cell death resistance controls intestinal humoral response zonation
IgA response is critical for intestinal immunity; however, the role of IgA in the germinal center (GC) is unknown. Here, Raso et al. reveal that the IgA B cell receptor (BCR) is required for Peyer’s patch (PP) GC B cell survival and selection into memory B cells and gut-homing plasma cells.