AI SummaryA recent study in France suggests that longer storage of red blood cells may improve the success of kidney transplants. Patients who received older blood had a 6% higher transplant survival rate after 5 years compared to those who received fresher blood. The study proposes that older blood may have immunomodulatory properties and be… Continue reading Ageing blood – kind of like ageing wine. The longer you age it, the better, says one study
Category: Immunology
Autoimmune diseases: Protein discovered as potential new target for therapies
AI SummaryA new immunoregulatory protein called ‘Rinl’ has been discovered, which could be linked to the development of autoimmune diseases like rheumatoid arthritis. This finding could lead to the development of new immunomodulatory therapies.Autoimmune diseases are complex illnesses, the causes of which are diverse and have not yet been fully explained. A research team has… Continue reading Autoimmune diseases: Protein discovered as potential new target for therapies
Vaccine Signals a New Treatment Option for Advanced Non-Small Cell Lung Cancer
AI SummaryA recent study found that a cancer vaccine called OSE2101 showed better overall survival rates compared to chemotherapy for patients with non-small-cell lung cancer who had become resistant to immunotherapy. The vaccine targets specific proteins found on cancer cells and instructs immune cells to kill them. This provides new hope for patients with advanced… Continue reading Vaccine Signals a New Treatment Option for Advanced Non-Small Cell Lung Cancer
The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2
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CPT1A-mediated fatty acid oxidation confers cancer cell resistance to immune-mediated cytolytic killing
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Light-inducible T cell engagers trigger, tune, and shape the activation of primary T cells
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Multivalent virus-like epitope display amplifies BCR signaling independent of avidity
AI SummaryDisplaying multivalent epitopes on viral-sized particles triggers a unique mode of B cell receptor signaling that enhances B cell activation, survival, and proliferation without the need for T cell co-stimulation.We show that multivalent epitope display on the surface of viral-sized particles functions as a ‘stand-alone’ danger signal by evading inhibitory pathways to trigger a… Continue reading Multivalent virus-like epitope display amplifies BCR signaling independent of avidity
Molecular pathways underlying lung-brain axis signaling in asthma: relevance for psychopathology and neuroinflammation
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Congratulations Amy Dashwood!
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The Spectrum of Environmental Disparities in Asthma
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