Category: Immunology

Distinct functions of CD4+ and CD8+ regulatory T cells in autoimmunity

Using a novel human tonsil immune organoid system, Chen et al. demonstrate that by controlling autoreactive humoral and cellular responses, human CD4+ regulatory T cells (Treg cells) and CD8+ Treg cells cooperatively restrain the otherwise uncontrolled autoimmune disease progression. This is a preview of subscription content, access via your institution Access options Access through your… Continue reading Distinct functions of CD4+ and CD8+ regulatory T cells in autoimmunity

Immune environment found to influence success of leukemia immunotherapy

A research team from Columbia Engineering and the Irving Institute for Cancer Dynamics made a pivotal discovery in the field of cancer immunotherapy. In a paper published today in Science Immunology, the team identified a specific population of immune cells that play a critical role in successful treatment of relapsed acute myeloid leukemia (AML). This work was in collaboration with… Continue reading Immune environment found to influence success of leukemia immunotherapy

Researchers identify key factors for successful donor lymphocyte infusion in AML patients

Dana-Farber Cancer Institute researchers have identified factors that determine whether donor lymphocyte infusion (DLI), a standard therapy for patients with acute myeloid leukemia (AML) who have relapsed after allogenic hematopoietic stem cell transplant, will successfully move the patient into remission. The team identified that a key cell type in the DLI product and features of the… Continue reading Researchers identify key factors for successful donor lymphocyte infusion in AML patients

AI-based blood test could revolutionize diagnosis of Long Covid in children

One day Long Covid in children could be objectively diagnosed with a blood test, thanks to the help of Artificial Intelligence (AI). In fact, a study by the Università Cattolica del Sacro Cuore, Rome campus – Fondazione Policlinico Universitario Agostino Gemelli IRCCS and the Ospedale Pediatrico Bambino Gesù IRCCS, has highlighted the molecular signature of… Continue reading AI-based blood test could revolutionize diagnosis of Long Covid in children

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Categorized as Immunology

NIAID workshop on infections and autoimmune diseases

On 11–12 September 2024, the National Institute of Allergy and Infectious Diseases (NIAID) convened experts to discuss associations between microorganisms and the development of autoimmune diseases. This is a preview of subscription content, access via your institution Access options Access through your institution Change institution Buy or subscribe /* style specs start */ /* style… Continue reading NIAID workshop on infections and autoimmune diseases

ImmunOctoberfest reloaded

On 23–26 September 2024, the second ImmunOctoberfest conference took place in Raitenhaslach, Germany, and brought together scientists from all over the world to catch up on recent advances in ‘Bridging Innovation and Translation in T cell Immunotherapy’. This is a preview of subscription content, access via your institution Access options Access through your institution Change… Continue reading ImmunOctoberfest reloaded