Researchers from the National Healthcare Group (NHG)’s Institute of Mental Health (IMH) and Agency for Science, Technology and Research (A*STAR) have made strides in understanding the connection between the immune system and resistance to antipsychotic medications in schizophrenia, using changes in immune cell populations to predict potential treatment resistance and initiate the most appropriate treatment… Continue reading Immune system changes may predict antipsychotic resistance in schizophrenia Scientis…
Category: Immunology
AstraZeneca’s Pioneering Research in Heart Failure and ATTR-CM
Thought LeaderMina MakarSenior Vice President, Global CVRMAstraZeneca NewsMedical spoke with Mina Makar, Senior Vice President of Global CVRM at AstraZeneca, about groundbreaking research in Heart Failure and Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM). Mina shares insights on AstraZeneca’s mission to address unmet needs in cardiovascular care and the future of personalized medicine. Firstly, please introduce yourself and tell us… Continue reading AstraZeneca’s Pioneering Research in Heart Failure and ATTR-CM
Novel method to fight cancer uses ultrasound-guided microbubbles
A new paper by a team of Concordia researchers from the departments of Biology and Physics proposes a novel method of fighting cancer tumors that uses ultrasound-guided microbubbles – a technology already widely used in medical imaging and drug delivery. Writing in the journal Frontiers in Immunology, the researchers describe a process that uses ultrasound to modify the behavior of… Continue reading Novel method to fight cancer uses ultrasound-guided microbubbles
Study uncovers why lupus patients have weaker response to COVID-19 vaccines
A recent study by Emory University researchers provides new insights into why the mRNA vaccines developed to fight COVID-19 in 2021 are less effective in patients with autoimmune diseases. By providing insights into the cellular processes behind that lessened protection, the new study published in Nature Immunology, highlights that lupus patients may require tailored vaccination… Continue reading Study uncovers why lupus patients have weaker response to COVID-19 vaccines
Drug in breast cancer trials shows potential for treating blood cancers
Two new studies led by researchers at Washington University School of Medicine in St. Louis have identified a possible way to block the progression of several forms of blood cancer using a drug already in clinical trials against breast cancer. The studies – both conducted in patient samples and animal models – found that inhibiting… Continue reading Drug in breast cancer trials shows potential for treating blood cancers
New research identifies key subtype of bacterial vaginosis that increases chlamydia risk
Women who develop bacterial vaginosis (BV) often later acquire chlamydia, a common and potentially serious sexually transmitted bacterial infection. Now, researchers at Albert Einstein College of Medicine, Roswell Park Comprehensive Cancer Center, and the Icahn School of Medicine at Mount Sinai have found that BV actually consists of two subtypes-one of which significantly increases the… Continue reading New research identifies key subtype of bacterial vaginosis that increases chlamydia risk
Crucial role of the cGAS N terminus in mediating flowable and functional cGAS–DNA condensate formation via DNA interactions
New target identified for potential colorectal cancer treatment
Colorectal cancer (CRC) is a type of cancer that begins in the colon (large intestine) or rectum, which are parts of the digestive system. It typically starts as abnormal growths called polyps that form in the lining of the colon or rectum. Over time, some of these polyps can become cancerous if left untreated. CRC… Continue reading New target identified for potential colorectal cancer treatment
Primary Antibody Deficiencies: Curation Of Gene-Disease Relationships Using A ClinGen Validation Framework
A cocktail of kinase inhibitors that enhance the antitumor effects of CAR-T cell therapy
In an unbiased high-throughput screen of 800 kinase inhibitors, we identified a cocktail of kinase inhibitors that increase the frequency of T memory stem cells for CAR-T cell therapy, resulting in improved antitumor effects both in vitro and in mouse models. This is a preview of subscription content, access via your institution Access options Access… Continue reading A cocktail of kinase inhibitors that enhance the antitumor effects of CAR-T cell therapy