Category: Biochemistry

Abstract Electrocatalysis of small gas molecules driven by renewable energy sources offers a promising route to carbon-neutral fuels and chemicals. Such small-molecule conversion reactions rely on water as a source of protons and electrons, however, thus limiting energy and power densities owing to the low solubility of gas molecules in water. The oxygen reduction reaction… Continue reading Enhanced activity for the oxygen reduction reaction in microporous water

Abstract Methanol, an organic one-carbon (C1) compound, represents an attractive alternative carbon source for microbial fermentation. Despite considerable advancements in methanol utilization by prokaryotes such as Escherichia coli, engineering eukaryotic model organisms such as Saccharomyces cerevisiae into synthetic methylotrophs remains challenging. Here, an engineered module circuit strategy combined with adaptive laboratory evolution was applied to… Continue reading Reprogramming methanol utilization pathways to convert Saccharomyces cerevisiae to a synthetic methylotroph