Development, biological evaluation, and molecular modelling of some benzene-sulfonamide derivatives as protein tyrosine phosphatase-1B inhibitors for managing diabetes mellitus and associated metabolic disorders

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* Corresponding authors

a Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt
E-mail: Ranza.el-rayes@pharm.suez.edu.eg
Fax: +20 064 3230741
Tel: +20 102 548 8849

b Department of Medicinal Chemistry, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt

c Department of Medicinal Chemistry, Faculty of Pharmacy, Galala University, New Galala 43713, Egypt

d Department of Chemistry, College of Sciences, University of Sharjah, Sharjah, United Arab Emirates

e Department of Chemistry, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt

f Department of Zoology, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt

g Department of Pharmaceutics, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt

h Department of Biochemistry, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt

i Department of Pharmacology and Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt

j Pharmaceutical Organic Chemistry Department, College of Pharmacy, Al-Ayen University, Dhi-Qar, Iraq