Triton X-100-treated virus-based ELLA demonstrates discordant antigenic evolution of influenza B virus hemagglutinin and neuraminidase

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This study explores the antigenic evolution of the hemagglutinin and neuraminidase proteins of influenza B virus using Triton X-100-treated virus-based enzyme-linked lectin assay (ELLA). The researchers found that the antigenic evolution of these two proteins is discordant, highlighting the importance of understanding the dynamics of both hemagglutinin and neuraminidase in influenza B virus evolution. The study's findings have implications for the development of vaccines and antiviral therapies targeting influenza B virus.

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