AI Summary
This article explores the replication kinetics of pathogenic Eurasian orthohantaviruses in human mesangial cells. Eurasian orthohantaviruses are known to cause hemorrhagic fever with renal syndrome (HFRS), which is characterized by acute kidney injury (AKI). The study aims to understand how these viruses replicate in human cells, potentially shedding light on the mechanisms behind HFRS and AKI. This research is significant for advancing our knowledge of orthohantavirus pathogenesis and could lead to the development of improved treatment strategies.
Eurasian pathogenic orthohantaviruses cause hemorrhagic fever with renal syndrome (HFRS) characterized by acute kidney injury (AKI). The virulence of orthohantaviruses varies enormously and direct infection of…