AI Summary
The article discusses the importance of identifying characteristics of cancer cells recognized by the immune system as potential targets for personalized cancer immunotherapy. Scientists have developed a method using mass spectroscopy to detect tumor-specific 'neoepitopes', which are low abundance protein fragments. This method is highly sensitive and requires minimal sample material, allowing for the identification of personalized targets for immunotherapy.
What are the characteristics of a cancer cell that are recognized by the immune system? Knowledge of the potential target structures for the immune cells is a basic prerequisite for the development of personalized cancer immunotherapies. Scientists are publishing a highly sensitive method based on mass spectroscopy to identify such tumor-specific ‘neoepitopes’. The analytical method is designed to detect these low abundance protein fragments and requires minimal amounts of sample material.