AI Summary
This article investigates how mutations in the S-region of the hepatitis B virus (HBV) affect the production of HBsAg in HBsAg-negative HBV-infected patients. The study aims to understand the role of these mutations in occult HBV infection (OBI), which can lead to serious complications like liver cirrhosis and hepatocellular carcinoma. The findings may have implications for the diagnosis and treatment of OBI, potentially improving outcomes for affected patients.
Occult HBV infection (OBI) is a special form of hepatitis B virus (HBV) infection that may cause Liver cirrhosis and hepatocellular carcinoma, causing significant harm to patients. Given the insidious nature o…