AI Summary
The article discusses a study by Znamenskiy et al. that highlights the precise synaptic connectivity and functional specificity of parvalbumin-positive inhibitory neurons in the mouse visual cortex. The research demonstrates that these inhibitory neurons inhibit pyramidal cells that provide them with strong excitation and exhibit similar response patterns in vivo. This suggests a specific and detailed mechanism of recurrent inhibition in the visual cortex.
Znamenskiy et al. reveal unexpected precision of synaptic strength of parvalbumin-positive inhibitory neurons in the mouse visual cortex. By measuring their visual responses and synaptic connectivity, they show that PV+ cells preferentially inhibit those pyramidal cells that provide them with strong excitation and have similar patterns of responses in vivo.