AI Summary
This article discusses how structure-guided mutagenesis of Henipavirus receptor-binding proteins helps to identify the molecular determinants of receptor usage and antibody-binding epitopes. The research focuses on understanding the interactions between the virus and its host, as well as the potential targets for therapeutic interventions. The use of mutagenesis allows researchers to manipulate specific amino acids in the protein structure to determine their role in receptor binding and antibody recognition. This approach provides valuable insights into the biology of Henipaviruses and may lead to the development of new antiviral strategies.