RSC Med. Chem., 2023, 14,1114-1130
DOI: 10.1039/D3MD00010A, Research ArticleNguyen Dinh Thanh, Pham Hong Lan, Do Son Hai, Hoang Huu Anh, Nguyen Thi Kim Giang, Hoang Thi Kim Van, Vu Ngoc Toan, Nguyen Minh Tri, Duong Ngoc Toan
Substituted thioureas with 1,3-thiazole and D-glucose were gained from 2-amino-1,3-thiazoles and glucopyranosyl isocyanate. They had antimicrobial activity, some inhibiting S. aureus DNA gyrase, DNA Topo IV, and dihydrofolate reductase. IFD, MM-GBSA and MD were performed.
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Thiourea derivatives containing 4-arylthiazoles and D-glucose moiety: design, synthesis, antimicrobial activity evaluation, and molecular docking/dynamics simulations
