The bone transcription factor Osterix controls extracellular matrix- and node of Ranvier-related gene expression in oligodendrocytes

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Elbaz et al. show that Sp7 mediates the expression of genes required for node of Ranvier and brain ECM formation in mature oligodendrocytes. Moreover, Elbaz et al. show that Sp7 regulates ECM gene expression in a similar manner in oligodendrocytes and osteoblasts.