AI Summary
Young adult-born hippocampal neurons are crucial for mice's ability to differentiate between similar situations; their absence leads to contextual representations being dominated by landmarks, reminiscent of overgeneralization seen in anxiety and age-related disorders.
Tuncdemir et al. show that young adult-born hippocampal neurons are critical for mice’s ability to discriminate between similar situations. In the absence of these young neurons, contextual representations are dominated by landmarks, a situation that is reminiscent of the overgeneralization often found in anxiety and age-related disorders.