Secret vulnerabilities of cancer’s ‘death star’ revealed

AI Summary

Researchers have identified the allosteric control sites in the protein KRAS, which can be targeted for drug development in the fight against cancer. This discovery is expected to accelerate the development of safer and more effective cancer treatments.

Researchers have comprehensively identified the allosteric control sites found in the protein KRAS. These are highly sought after targets for drug development, representing secret vulnerabilities which can be exploited to control the effects of one of the most important causes of cancer. The study presents the first complete control map for any protein and is expected to greatly accelerate the discovery of safer, more effective cancer treatments.

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