AI Summary
A new bio-inspired drug shows promise in treating cancers with a deletion in the 9p21 section of their genomes. The drug improves immune cell effectiveness, slows tumor growth, extends lifespan, and enhances the efficacy of immunotherapy in mouse models of various cancers.
Cancers that have a deletion in the 9p21 section of their genomes tend to have worse outcomes for patients and increased resistance to immunotherapy. A new, bio-inspired drug restores the effectiveness of immune cells in fighting cancer. In mouse models of melanoma, bladder cancer, leukemia and colon cancer, the drug slows the growth of tumors, extends lifespan and boosts the efficacy of immunotherapy.