AI Summary
BAX plays a vital role in the death of retinal ganglion cells after optic nerve damage. The activation of BAX happens in two stages, involving the movement of latent BAX to the mitochondrial outer membrane.
Pro-apoptotic BAX is a central mediator of retinal ganglion cell (RGC) death after optic nerve damage. BAX activation occurs in two stages including translocation of latent BAX to the mitochondrial outer membr…