A WHO global framework to guide investigations into origins of potentially epidemic and pandemic pathogens

In outbreak situations involving a novel pathogen timely and coordinated response is crucial. The WHO Scientific Advisory Group for the Origins of Novel Pathogens recently released a global framework to guide future scientific investigations into the origin of emerging pathogens.

The risk of epidemics or pandemics caused by emerging or re-emerging pathogens remains a constant global threat. The COVID-19 pandemic1,2, as well as recurrent outbreaks of Ebola, Marburg, mpox, and other viruses are stark reminders of this. When outbreaks occur, understanding the origins of the pathogens and their pathways into the human population is critical. This knowledge not only guides the immediate public health response by identifying at-risk populations and transmission dynamics, it also informs epidemic and pandemic preparedness efforts, reducing the likelihood of future re-emergence.

The need to understand the origins of novel pathogens

In November 2021, the World Health Organization (WHO) appointed 27 scientists with a diverse range of appropriate expertise (acting in an individual capacity) to advise the Organization on technical and scientific considerations

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Categorized as Virology

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