Pengfei Yang is professor of neurosurgery and executive director of the neurovascular centre at Changhai Hospital, Naval Medical University (Shanghai, China). He obtained his medical degree from Zhejiang University (Hangzhou, China) and did his postdoctoral research on interventional neuroradiology at the University of Wisconsin-Madison (Madison, WI, USA). He leads a series of trials focusing on endovascular treatment of neurovascular diseases, including DIRECT-MT, ENCHANTED-2/MT, MAGIC-MT, and PROTECT-MT.