Human VCP mutant ALS/FTD microglia display immune and lysosomal phenotypes independently of GPNMB

🔗 Access full article via BMC Molecular Neurodegeneration

Microglia play crucial roles in maintaining neuronal homeostasis but have been implicated in contributing to amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). However, the role of microgli…