AI Summary
This article discusses the discovery and optimization of a series of vinyl sulfoximine-based analogues as potent Nrf2 activators for the treatment of multiple sclerosis. The research focuses on developing new molecules that can activate Nrf2, a protein that plays a key role in protecting cells from oxidative stress and inflammation. The goal is to identify compounds that can effectively target Nrf2 and potentially provide a new treatment option for multiple sclerosis.