When a double negative is not a positive: Autoantibodies against IL-10 in patients with inflammatory bowel disease

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This article discusses the presence of autoantibodies against interleukin-10 (IL-10) in patients with inflammatory bowel disease. IL-10 is an anti-inflammatory cytokine that plays a crucial role in regulating the immune system. The existence of autoantibodies against IL-10 indicates a dysregulation in the immune response, potentially leading to increased inflammation in patients with inflammatory bowel disease. This finding highlights the importance of understanding the role of IL-10 and autoimmunity in the pathogenesis of inflammatory bowel disease.

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