AI Summary
This article discusses the use of genetically encoded Trensor circuits to report the treatment of HeLa cells with polyplexed plasmid DNA and small-molecule transfection modulators. The focus is on developing a system to monitor and modulate gene expression in cells through specific genetic circuits. This research has the potential to advance our understanding of gene expression regulation and may lead to new therapeutic strategies for gene therapy or disease treatment. Summary: The article explores the application of genetically encoded Trensor circuits for monitoring and modulating gene expression in HeLa cells treated with polyplexed plasmid DNA and small-molecule transfection modulators. The research has implications for gene therapy and disease treatment strategies.