Low cortisol, hair-trigger stress response in the brain may underlie Long COVID

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Summary: An animal study suggests that exposure to immune-stimulating proteins from COVID-19 can lead to lower cortisol levels, brain inflammation, and increased sensitivity to stress. This may contribute to the development of long COVID symptoms.

A new animal study shows that exposure to immune-stimulating proteins left behind by COVID-19 leads to lower cortisol, brain inflammation and a heightened reaction to subsequent stressors.

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