[ASAP] Engineering a 3D Biomimetic Peptides Functionalized-Polyethylene Glycol Hydrogel Model Cocultured with Endothelial Cells and Astrocytes: Enhancing In Vitro Blood–Brain Barrier Biomimicry

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The title suggests a study focused on engineering a 3D biomimetic peptides functionalized-polyethylene glycol hydrogel model that is cocultured with endothelial cells and astrocytes. The research aims to enhance in vitro blood-brain barrier biomimicry, which can have significant implications for studying drug delivery and diseases affecting the brain. The use of biomimetic peptides and the coculture of different cell types are likely to improve the model's resemblance to the blood-brain barrier, potentially leading to more accurate and effective testing of drugs and treatments.

Molecular PharmaceuticsDOI: 10.1021/acs.molpharmaceut.4c00599

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