TWiV 1133: Gain of function makes us safer

AI Summary

This content is a podcast episode discussing various virology-related topics, including cases of measles in Brooklyn NY and Washington DC, the stalling of global childhood vaccination efforts, licenses H5N1 vaccines protecting against circulating strains, and a new BSL-2 proxy virus for SARS-CoV-2 neutralization assays. Deep mutational scanning reveals functional constraints and antibody-escape potential of the Lassa virus glycoprotein complex. The episode also features weekly picks and links to related research articles.

TWiV reviews cases of measles in Brooklyn NY and Washington DC, stalling of global childhood vaccination, licenses H5N1 vaccines protect against circulating strains, viruses traveling without passports. OC43 SARS-CoV- 2 spike replacement virus as an improved BSL-2 proxy virus for SARS-CoV-2 neutralization assays, and deep mutational scanning reveals functional constraints and antibody-escape potential of Lassa virus glycoprotein complex.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

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Download TWiV 1133 (86 MB .mp3, 119 min)
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Weekly Picks

Dickson – Elemental sulfur found on Mars
Kathy – Lennette Lectures at ASV, including Gail Wertz, ASV 2024
Rich – Electricity maps (Opinions: Nuclear Waste Is Misunderstood; Should We Be Worried About Nuclear Waste?)
Alan – Nature sent an investigative reporter to a predatory conference
Vincent – Coal-filled trains are likely sending people to the hospital

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

The post TWiV 1133: Gain of function makes us safer first appeared on This Week in Virology.

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