AI Summary
The article explores the role of stress granules (SGs) in neurodegenerative diseases, highlighting how their dysregulation can lead to various conditions. The authors discuss the dual roles of SGs as both protective responses to stress and contributors to disease progression, offering insights into therapeutic strategies targeting SGs. This research is significant for understanding the mechanisms underlying neurodegenerative diseases and developing novel treatments.
Although stress granules (SGs) form as a protective response to stress, their dysregulation contributes to various neurodegenerative diseases. Cui et al. review their dual roles in diseases as both “friends” and “foes,” shedding light on potential therapeutic strategies targeting SGs.