AI Summary
Researchers have identified a protein called FOXO1 that improves the survival and function of CAR T cells, potentially leading to more effective CAR T cell therapies and expanding their use in difficult-to-treat cancers.
CAR T cell therapy has revolutionized the way certain types of cancer are treated, and the longer those CAR T cells live in a patient’s body, the more effectively they respond to cancer. Now, researchers have found that a protein called FOXO1 improves the survival and function of CAR T cells, which may lead to more effective CAR T cell therapies and could potentially expand its use in difficult-to-treat cancers.