AI Summary
researchers successfully fabricated a polysaccharide-based nanocomposite membrane with high wet mechanical properties for bone repair. Through the use of bacterial cellulose nanofibers, the membrane was shown to possess a nanoscale network structure that provided superior mechanical properties compared to other competitors. This study offers a promising approach to enhancing the performance of polysaccharide-based membranes, which could have significant implications for their use in tissue repair applications.
Currently, membrane materials play an important role in tissue repair, especially polysaccharide-based membranes, attracting much attention due to their excellent biological properties. However, poor mechanical properties of polysaccharide-based membranes under wet conditions severely limit their in vivo applications. The fabrication of polysaccharide-based membranes with both robust wet mechanical properties and excellent biological properties remains challenging and is worth exploring.
Researchers at the University of Science and Technology of China recently published a research article in the National Science Review, attempting to address this challenge. They proposed a bioinspired mechanical reinforcement strategy based on heterogeneous crosslink-and-hydration (HCH) of molecular/nanoscale dual-network.
By the easy chemical principle (Ca2+ crosslinking and water molecule invasion), researchers can regulate the heterogeneity of the structure and composition of targeted nanocomposite materials. Here, the