AI Summary
This article discusses how POU-HD transcription factors can hinder the replication efficiency of various human papillomavirus genomes. HPV is a DNA virus that infects epithelial cells, and replication begins at a specific origin site. The presence of POU-HD TFs can negatively impact this replication process.
Human papillomavirus (HPV) is a double-stranded DNA virus that infects cutaneous and mucosal epithelial cells. HPV replication initiates at the origin (ori), located within a noncoding region near the major ea…