AI Summary
This review discusses the mechanisms of sex differences in Alzheimer's disease, exploring how sex hormones and chromosomes may impact inflammation, metabolism, and autophagy in aging. It highlights the potential biological influences that contribute to distinct disease patterns in men and women.
This review by Lopez-Lee and Torres et al. summarizes sex-specific differences in AD and potential biological mechanisms and discusses how sex hormones and chromosomes may influence inflammation, metabolism, and autophagy in aging, contributing to distinct disease patterns in men and women.