AI Summary
This article discusses how cortical electrical stimulation affects various types of neurons in awake animals. The study found that increasing stimulation amplitude recruits a distributed population of excitatory neurons, while inhibitory neurons are recruited closer to the electrode. Additionally, the activity level of excitatory neurons before stimulation strongly influences their evoked responses. This research provides insights into how different types of neurons are activated during cortical electrical stimulation in awake mammals.
How does cortical electrical stimulation affect different types of neurons in awake animals? The authors show that increasing stimulation amplitude recruits a distributed population of excitatory neurons but recruits inhibitory neurons closer to the electrode. Furthermore, evoked responses in excitatory neurons are strongly influenced by their pre-stimulus activity level.