AI Summary
University of Virginia researchers have found that a specific bacterium found in fermented foods and yogurt, called Lactobacillus, plays a role in managing stress and could potentially prevent depression and anxiety. This discovery opens up new possibilities for the development of therapies to treat mental health conditions. The research focuses on understanding the impact of individual microbes in the body and could lead to the development of new treatments for various diseases.
University of Virginia School of Medicine researchers have discovered how Lactobacillus, a bacterium found in fermented foods and yogurt, helps the body manage stress and may help prevent depression and anxiety. The findings open the door to new therapies to treat anxiety, depression and other mental-health conditions.
Image Credit: UVA Health
The new research from UVA’s Alban Gaultier, PhD, and collaborators is notable because it pinpoints the role of Lactobacillus, separating it out from all the other microorganisms that naturally live in and on our bodies. These organisms are collectively known as the microbiota, and scientists have increasingly sought to target them to battle disease and improve our health. UVA’s new research represents a major step forward in that effort, providing scientists an innovative new approach to understand the role of individual microbes that could facilitate the development of new treatments and cures for a wide variety of diseases, both mental and physical.
“Our discovery illuminates how gut-resident Lactobacillus influences mood disorders, by tuning the immune system,” said Gaultier, of UVA’s Department of Neuroscience, the Center for Brain Immunology and Glia (BIG Center) and the TransUniversity Microbiome Initiative. “Our research could pave the way towards discovering much-needed therapeutics for anxiety and depression.”
The microbiota and depression
Our guts are naturally home to countless bacteria, fungi, and viruses. There are more microorganisms living in and on us than there are cells in our bodies. That may sound disgusting, even alarming, but scientists have increasingly realized that these tiny organisms and their endless interactions are