AI Summary
Nanozymes, specifically metal-organic frameworks (MOFs), have emerged as promising alternatives to natural enzymes due to their high stability and catalytic activity. This paper reviews the role of MOF-based nanozymes in bacterial detection and treatment, highlighting their potential for broader clinical applications in addressing medical challenges.
The high efficiency and specificity of enzymes make them play an important role in life activities, but the high cost and low stability of natural enzymes severely limit their application. In recent years, nanozymes have emerged as compelling alternatives to natural enzymes, finding utility across diverse domains, including biosensing, antibacterial interventions, cancer treatment, and environmental preservation. Nanozymes are characterized by their remarkable attributes, encompassing high stability, cost-effectiveness, large surface area, and robust catalytic activity. Within the contemporary scientific landscape, metal-organic frameworks (MOFs) have garnered considerable attention, primarily due to their versatile applications, spanning catalysis. Notably, MOFs serve as scaffolds for the development of nanozymes, particularly in the context of bacterial detection and treatment. This paper presents a comprehensive review of recent literature pertaining to MOFs and their pivotal role in bacterial detection and treatment. We explored the limitations and prospects for the development of MOF-based nanozymes as a platform for bacterial detection and therapy, and anticipate their great potential and broader clinical applications in addressing medical challenges. Keywords: MOFs, Nanozymes, Sensor, Bacterial, Antibacterial