Researchers identify ‘switch’ to activate cancer cell death

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Researchers have discovered a mechanism to activate a cell receptor called Fas, which can induce cell death. This finding has potential implications in enhancing cancer treatments and extending CAR T-cell therapy to solid tumors.

A research team has identified a crucial mechanism on a specific cell receptor that can cause cells to self-destruct. Being able to activate the receptor — Fas — and trigger cell death could open the door for improved cancer treatments. Modulating Fas may also extend the benefits of chimeric antigen receptor (CAR) T-cell therapy to solid tumors.

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