An advance in cryo-EM could be a significant boon for research on potential cancer therapies

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A new technique allows for clearer imaging of small protein molecules using cryo-electron microscopy, which is important for drug research.

A technology called cryo-electron microscopy enables scientists to see the atomic structure of biological molecules in high resolution. But to date, it has been ineffective for imaging small molecules. A team of biochemists devised a solution that makes it possible to hold small protein molecules in place while they’re being imaged, which will enable cryo-EM to produce much clearer images of such molecules. The advance is significant because small and medium-sized protein molecules are an area of focus in research on potential new drugs for cancer and other diseases.

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