AI Summary
Combined cognitive rehabilitation and exercise did not improve processing speed in individuals with progressive multiple sclerosis. However, further studies comparing interventions to a non-intervention group are needed to determine if meaningful improvements in processing speed are possible.
Combined cognitive rehabilitation plus exercise does not seem to improve processing speed in people with progressive multiple sclerosis. However, our sham interventions were not inactive. Studies comparing interventions with a non-intervention group are needed to investigate whether clinically meaningful improvements in processing speed might be attainable in people with progressive multiple sclerosis.