Overcoming the challenges to synthesising iron–sulfur proteins outside the glovebox

Iron–sulfur (Fe–S) proteins, essential to all life forms, are difficult to synthesise due to the complicated molecular machinery involved and sensitivity to oxygen . In a new study, a team of researchers devised an innovative protocol for synthesising mature Fe –S proteins by bringing together a recombinant sulfur assimilation (SUF) system and an oxygen-scavenging system .

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